2,5-二甲基四氢呋喃

2,5-二甲基四氢呋喃是一种有机化合物，化学式为C₆H₁₂O。它可由2,5-己二醇和苯磺酰氯、吡啶反应制得，^[1]或由2,5-己二酮在催化下氢化得到。^[2][3]它和三乙基硅烷在三(五氟苯基)硼催化下反应，可以得到三乙基(1-甲基戊氧基)硅烷。^[4]

2,5-二甲基四氢呋喃
识别
CAS号	1003-38-9  Y
SMILES	O1C(C)CCC1C
性质
化学式	C6H12O
摩尔质量	100.16 g·mol−1
若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

参考文献

1. Binch, H. (2001). Benzenesulfonyl Chloride. Encyclopedia of Reagents for Organic Synthesis. doi:10.1002/047084289x.rb022
2. Grochowski, Matthew R.; Yang, Weiran; Sen, Ayusman. Mechanistic Study of a One-Step Catalytic Conversion of Fructose to 2,5-Dimethyltetrahydrofuran. Chemistry - A European Journal, 2012. 18 (39). doi:10.1002/chem.201201522.
3. Hua, Manli; Song, Jinliang; Huang, Xin; Hou, Minqiang; Fan, Honglei; Zhang, Zhaofu; Wu, Tianbin; Han, Buxing. Support Effect of Ru Catalysts for Efficient Conversion of Biomass-Derived 2,5-Hexanedione to Different Products. ACS Catalysis, 2021. 11 (13). doi:10.1021/acscatal.1c00971.
4. Gevorgyan, Vladimir; Rubin, Michael; Benson, Sharonda; Liu, Jian-Xiu; Yamamoto, Yoshinori. A Novel B(C₆F₅)₃-Catalyzed Reduction of Alcohols and Cleavage of Aryl and Alkyl Ethers with Hydrosilanes. Journal of Organic Chemistry, 2000. 65 (19). doi:10.1021/jo000726d.