1-(2-联苯基)哌嗪是一种有机化合物，化学式为C16H18N2。它可由1-叔丁氧羰基-4-(2-溴苯基)哌嗪和苯硼酸在四(三苯基膦)钯催化下反应制得，[1]或由2-氨基联苯和二(氯乙基)胺盐酸盐在碳酸钾和碘化钾存在下反应得到。[2]它和N-苄基-6-溴己酰胺在碳酸钾存在下于乙腈中回流反应，可以得到N-苄基-(4-联苯-2-基)哌嗪己酰胺。[3]
Quick Facts 识别信息, CAS号 ...
1-(2-联苯基)哌嗪 |
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| CAS号 | 180698-18-4  Y |
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| 化学式 | C16H18N2 |
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| 摩尔质量 | 238.33 g·mol−1 |
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| 3D模型（JSmol） | |
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C3CNCCN3c1ccccc1-c2ccccc2
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InChI=1S/C16H18N2/c1-2-6-14(7-3-1)15-8-4-5-9-16(15)18-12-10-17-11-13-18/h1-9,17H,10-13H2 YKey:RKRVRTJVCWZOQS-UHFFFAOYSA-N Y
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Yu, Maolin; Daniels, Matthew H.; Harmange, Jean-Christophe P.; Tibbitts, Thomas T.; Ledeboer, Mark W.; Walsh, Liron; Mundel, Peter H.; Malojcic, Goran. Pyridazinone derivatives in the treatment of disease and their preparation. 2019 WO 2019055966 A2.
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