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治《诗经》，由医生中式顺天府乡试第十二名举人，成化二年丙戌科会试中式第五十二名，第三甲第十名进士[1]。授南京大理寺副，历寺正、江西按察佥事、贵州按察副使。
曾祖陈孚敏；祖陈纪；父陈茂；母钱氏；继母张氏。具庆下。妻吴氏。行二，兄琳，弟瑄。
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