原核延伸因子(英语:Prokaryotic elongation factors)是原核细胞进行原核翻译的过程中所需的三种延伸因子,分别被命名为:EF-Tu、EF-Ts及EF-G(其中EF-Tu和EF-Ts可复合为EF-T)。原核延伸因子的化学本质都是蛋白质。
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