酮醇酸还原异构酶（英语：ketol-acid reductoisomerase，EC 1.1.1.86 （页面存档备份，存于互联网档案馆））是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应：
| 酮醇酸还原异构酶 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| |||||||||
| 识别码 | |||||||||
| EC编号 | 1.1.1.86 | ||||||||
| CAS号 | 9075-02-9 | ||||||||
| 数据库 | |||||||||
| IntEnz | IntEnz浏览 | ||||||||
| BRENDA | BRENDA入口 | ||||||||
| ExPASy | NiceZyme浏览 | ||||||||
| KEGG | KEGG入口 | ||||||||
| MetaCyc | 代谢路径 | ||||||||
| PRIAM | 概述 | ||||||||
| PDB | RCSB PDB PDBj PDBe PDBsum | ||||||||
| 基因本体 | AmiGO / EGO | ||||||||
| |||||||||
酮醇酸还原异构酶还能将2-乙酰-2-羟基丁酸催化转化为2,3-二羟基-3-甲基戊酸。
参考文献
- Arfin SM, Umbarger HE. Purification and properties of the acetohydroxy acid isomeroreductase of Salmonella typhimurium. J. Biol. Chem. 1969, 244 (5): 1118–27. PMID 4388025.
- Hill RK, Sawada S and Arfin SM. Stereochemistry of valine and isoleucine biosynthesis. IV Synthesis, configuration, and enzymatic specificity of alpha-acetolactate and alpha-aceto-alpha-hydroxybutyrate. Bioorg. Chem. 1979, 8 (2): 175–189. doi:10.1016/0045-2068(79)90003-8.
- Kiritani K, Narise S and Wagner RP. The reductoisomerase of Neurospora crassa. J. Biol. Chem. 1966, 241: 2047–2051.
- Satyanarayana T, Radhakrishnan AN. Biosynthesis of valine and isoleucine in plants. 3. Reductoisomerase of Phaseolus radiatus. Biochim. Biophys. Acta. 1965, 110 (2): 380–8. PMID 5866387.
Wikiwand in your browser!
Seamless Wikipedia browsing. On steroids.
Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface.
Wikiwand extension is a five stars, simple, with minimum permission required to keep your browsing private, safe and transparent.
