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許多已確定的抗病毒化合物用於治療臨床研究中的其他感染，將被重新利用（英语：COVID-19 drug repurposing research）。 2019冠状病毒病药物研发的方式主要有两种：一种是药物再利用研究（英语：COVID-19 drug repurposing research），即考察已被批准用于治疗其他疾病的药物，
Lipinski CA, Reaume AG. High throughput in vivo phenotypic screening for drug repurposing: Discovery of MLR-1023 a novel insulin sensitizer and novel Lyn kinase
2174/1871520615666160504095040. Shirley, DA; Sharma, I; Warren, CA; Moonah, S. Drug Repurposing of the Alcohol Abuse Medication Disulfiram as an Anti-Parasitic Agent
1002/jmv.24736 PMID 27864902 Elfiky AA. Anti-HCV, nucleotide inhibitors, repurposing against COVID-19. Life Sci. 2020 May 1;248:117477. doi:10.1016/j.lfs
Krishna S, Augustin Y, Wang J, Xu C, Staines HM, Platteeuw H, et al. Repurposing Antimalarials to Tackle the COVID-19 Pandemic. Trends in Parasitology