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宫颈机能不全
Geijn HP. Final results of the Cervical Incompetence Prevention Randomized Cerclage Trial (CIPRACT): therapeutic cerclage with bed rest versus bed rest
或是不要。有些研究中，betamimetic有降低雙胞胎產婦早產的機率，但樣本數量過低，無法形成有力的結論。利用子宮頸環紮術（英语：Cervical cerclage）來避免早產的作法也不確定對多胞胎是否有效，原因仍然是因研究樣本太少。 多胞胎的早產也導致其出生体重過輕。
反覆流產
Obstetricians and, Gynecologists. ACOG Practice Bulletin No.142: Cerclage for the management of cervical insufficiency. Obstetrics and Gynecology. Feb 2014, 123
Obstetricians and, Gynecologists. ACOG Practice Bulletin No.142: Cerclage for the management of cervical insufficiency. Obstetrics and Gynecology. Feb 2014, 123