27-羟基胆固醇（英语：27-Hydroxycholesterol，缩写27-HC）是一种内源性的氧化胆固醇，有着多重生物学功能，包括选择性雌激素受体调节物（SERM）活性，肝X受体（LXR）激动剂[1]等，由细胞色素P450氧化酶CYP27A1催化胆固醇生成[1]。
| 27-羟基胆固醇 | |
|---|---|
| |
| IUPAC名 (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,6R)-7-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol | |
| 系统名 Cholest-5-ene-3β,27-diol | |
| 识别 | |
| CAS号 | 20380-11-4 |
| PubChem | 123976 |
| ChemSpider | 110495 |
| SMILES |
|
| IUPHAR配体 | 2752 |
| 性质 | |
| 化学式 | C27H46O2 |
| 摩尔质量 | 402.65 g·mol−1 |
| 若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。 | |
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