雌甾四烯

雌甾四烯
临床资料
ATC码	未分配;
识别信息
	IUPAC命名法 (8S,9S,13R,14S)-13-methyl-6,7,8,9,11,12,14,15-octahydrocyclopenta[a]phenanthren-3-ol; OR; (1S,10S,11S,15R)-15-methyltetracyclo[8.7.0.02,7.011,15]heptadeca-2,4,6,13-tetraen-5-ol; ;
CAS号	1150-90-9
PubChem CID	101988;
CompTox Dashboard（英语：CompTox Chemicals Dashboard） (EPA)	DTXSID80921587 ;
化学信息
化学式	C18H22O
摩尔质量	254.37 g·mol−1
3D模型（JSmol（英语：JSmol））	交互式图像;
	SMILES C[C@]12CC[C@H]3[C@H]([C@@H]1CC=C2)CCC4=C3C=CC(=C4)O;

雌甾四烯（英语：estratetraenol）又称雌四烯醇、雌甾-1,3,5(10),16-麦角甾四烯-3-醇（estra-1,3,5(10),16-tetraen-3-ol），是一种成年女子^[1]分泌的化学物质，会对包括人类在内的灵长类动物^[2] 产生与信息素（费洛蒙）相关的作用^[3]^[4]^[5]^[6]。雌四烯醇最可能是人类女性费洛蒙、性激素雌二醇的代谢物，目前尚没有表现出任何已知的雌激素活化作用。

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参考资料

[1]
Thysen, B; Elliott, WH; Katzman, PA. Identification of estra-1,3,5(10),16-tetraen-3-ol (estratetraenol) from the urine of pregnant women (1). Steroids. 1968, 11 (1): 73–87. PMID 4295975.
[2]
Laska, M; Wieser, A; Salazar, LT. Sex-specific differences in olfactory sensitivity for putative human pheromones in nonhuman primates. Journal of comparative psychology (Washington, D.C. : 1983). 2006, 120 (2): 106–12. PMID 16719588. doi:10.1037/0735-7036.120.2.106.
[3]
Jacob, S; Hayreh, DJ; McClintock, MK. Context-dependent effects of steroid chemosignals on human physiology and mood. Physiology & behavior. 2001, 74 (1-2): 15–27. PMID 11564447.
[4]
Savic, I; Berglund, H; Gulyas, B; Roland, P. Smelling of odorous sex hormone-like compounds causes sex-differentiated hypothalamic activations in humans. Neuron. 2001, 31 (4): 661–8. PMID 11545724. doi:10.1016/S0896-6273(01)00390-7.
[5]
Berglund, H; Lindström, P; Savic, I. Brain response to putative pheromones in lesbian women. Proceedings of the National Academy of Sciences of the United States of America. 2006, 103 (21): 8269–74. PMC 1570103 . PMID 16705035. doi:10.1073/pnas.0600331103.
[6]
Berglund, H; Lindström, P; Dhejne-Helmy, C; Savic, I. Male-to-female transsexuals show sex-atypical hypothalamus activation when smelling odorous steroids. Cerebral cortex (New York, N.Y. : 1991). 2008, 18 (8): 1900–8. PMID 18056697. doi:10.1093/cercor/bhm216.

参见

信息素
雄甾二烯酮
雄三酮
雄甾烯醇
雄甾烯酮
雄甾酮
脱氢反雄甾酮

[1] [1]
Thysen, B; Elliott, WH; Katzman, PA. Identification of estra-1,3,5(10),16-tetraen-3-ol (estratetraenol) from the urine of pregnant women (1). Steroids. 1968, 11 (1): 73–87. PMID 4295975.

[2] [2]
Laska, M; Wieser, A; Salazar, LT. Sex-specific differences in olfactory sensitivity for putative human pheromones in nonhuman primates. Journal of comparative psychology (Washington, D.C. : 1983). 2006, 120 (2): 106–12. PMID 16719588. doi:10.1037/0735-7036.120.2.106.

[3] [3]
Jacob, S; Hayreh, DJ; McClintock, MK. Context-dependent effects of steroid chemosignals on human physiology and mood. Physiology & behavior. 2001, 74 (1-2): 15–27. PMID 11564447.

[4] [4]
Savic, I; Berglund, H; Gulyas, B; Roland, P. Smelling of odorous sex hormone-like compounds causes sex-differentiated hypothalamic activations in humans. Neuron. 2001, 31 (4): 661–8. PMID 11545724. doi:10.1016/S0896-6273(01)00390-7.

[5] [5]
Berglund, H; Lindström, P; Savic, I. Brain response to putative pheromones in lesbian women. Proceedings of the National Academy of Sciences of the United States of America. 2006, 103 (21): 8269–74. PMC 1570103 . PMID 16705035. doi:10.1073/pnas.0600331103.

[6] [6]
Berglund, H; Lindström, P; Dhejne-Helmy, C; Savic, I. Male-to-female transsexuals show sex-atypical hypothalamus activation when smelling odorous steroids. Cerebral cortex (New York, N.Y. : 1991). 2008, 18 (8): 1900–8. PMID 18056697. doi:10.1093/cercor/bhm216.

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