校对[1]英语Proofreading)是指DNA复制过程中的错误检测和修正,主要具有此能力的酵素DNA聚合酶

  • 细菌中所有三种DNA聚合酶(I、II、III)都有3'到5'方向的外切酶活性(与外切酶相同的功能);
  • 真核生物体内则只有参与延长序列(γ、δ与ε)作用的聚合酶有此功能;同样是具有3'到5'方向的外切酶活性。

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