大环化合物

大环化合物（英语：Macrocycle）指环里有12个或以上成员环的有机化合物，常见例子有卟啉、冠醚以及环糊精和杯芳烃等^[3]。

红霉素，一种天然的大环内酯类抗生素，带有一个十四元环^[1]

尿卟啉原Ⅲ，卟啉生物合成的前体物质^[2]

大环冠醚18-冠-6与钾离子(K⁺)组成的复合物

参考文献

1. Hamilton-Miller, JM. Chemistry and Biology of the Polyene Macrolide Antibiotics. Bacteriological Reviews. 1973, 37 (2): 166–196. PMC 413810 . PMID 4578757.
2. Paul R. Ortiz de Montellano. Wiley Encyclopedia of Chemical Biology. John Wiley & Sons. 2008. ISBN 978-0470048672. doi:10.1002/9780470048672.wecb221. |chapter=被忽略 (帮助)
3. Zhichang Liu, Siva Krishna Mohan Nalluria, J. Fraser Stoddart. Surveying macrocyclic chemistry: from flexible crown ethers to rigid cyclophanes. Chemical Society Reviews. 2017, 46 (9): 2459–2478. PMID 28462968. doi:10.1039/c7cs00185a.

延伸阅读

• Chambron, J-C.; Dietrich-Buchecker, C.; Hemmert, C.; Khemiss, A-K.; Mitchell, D.; Sauvage, J-P.; Weiss, J. Interlacing molecular threads on transition metals (PDF). Pure Appl. Chem. 1990, 62 (6): 1027–34 [2020-01-30]. doi:10.1351/pac199062061027. （原始内容存档 (PDF)于2016-08-19）.
• Iyoda, Masahiko; Yamakawa, Jun; Rahman, M. Jalilur. Conjugated Macrocycles: Concepts and Applications. Angewandte Chemie International Edition. 2011-11-04, 50 (45): 10522–10553. ISSN 1521-3773. PMID 21960431. doi:10.1002/anie.201006198 （英语）.