大桑格雷地区(英语:Sangre Grande region)是特立尼达和多巴哥的9个地区之一,位于特立尼达岛东北部,北邻加勒比海,东临加勒比海,南毗马亚罗-里奥克拉罗地区,西接图纳普纳-皮亚尔科地区库瓦-塔瓦基特-塔尔帕罗地区,首府设于大桑格雷,面积927平方公里,2011年人口75,766,人口密度每平方公里82人。

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