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化合物 来自维基百科,自由的百科全书
去炎松(英语:triamcinolone)又叫氟羟氢化泼尼松、曲安西龙,是长效合成的皮质类固醇,可口服、注射、吸入或制成软膏外用。可用来治疗湿疹、银屑病、关节炎、过敏、溃疡性大肠炎(Ulcerative colitis)、红斑性狼疮、交感性眼炎、巨大细胞动脉炎(Giant cell arteritis)、葡萄膜炎(Uveitis)、眼炎的治疗,玻璃体切除时的呈像及预防哮喘等,但其无法在哮喘发作后作出有效治疗[1][2][3]。
临床资料 | |
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商品名 | Kenalog |
其他名称 | Click show to see
(8S,9R,10S,11S,13S,14S,16R,17S)-9-fluoro-11,16,17-trihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one; (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-13,14,17-trihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one |
AHFS/Drugs.com | Monograph |
怀孕分级 |
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给药途径 | Oral, topical, IM, intra-articular, intrasynovial |
ATC码 | |
法律规范状态 | |
法律规范 |
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药物动力学数据 | |
血浆蛋白结合率 | 68% |
药物代谢 | Hepatic |
生物半衰期 | 88 minutes |
排泄途径 | Fecal and renal |
识别信息 | |
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CAS号 | 124-94-7 |
PubChem CID | |
IUPHAR/BPS | |
DrugBank | |
ChemSpider | |
UNII | |
KEGG | |
ChEBI | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.004.290 |
化学信息 | |
化学式 | C21H27FO6 |
摩尔质量 | 394.434 g/mol |
3D模型(JSmol) | |
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