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OpisThe steps of regenerative medicine..jpg |
English: The production of cellular therapies requires the optimization of four steps: first, isolating and culturing cells that can be readily obtained from a patient in a non-invasive fashion. Second, the reprogramming of these cells into a pluripotent state. Third, the directed differentiation of those patient-specific pluripotent cells into the cell type relevant to their disease. And, fourth, techniques for repairing any intrinsic disease-causing genetic defects and transplantation of the repaired, differentiated cells into the patient. Notably, these disease-relevant patient cells can also be used for in vitro disease modeling which may yield new insights into disease mechanisms and drug discovery. |
Datum | Published September 30, 2008. |
Vir |
[1] Direct
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Avtor | Rodolfa, K.T., Inducing pluripotency (September 30, 2008), StemBook, ed. The Stem Cell Research Community, StemBook, doi/10.3824/stembook.1.22.1, http://www.stembook.org. |
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trenutno | 20:57, 5. april 2013 | ![]() | 432 × 430 (55 KB) | Smallbot | Uploading CC-BY images from the the StemBook http://www.stembook.org/ 114/173 |
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