Charles Louis Frederick of Mecklenburg (23 February 1708 – 5 June 1752) was a prince in the House of Mecklenburg-Strelitz. He is also known as Prince of Mirow. He never reigned.

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Two of his sons, Adolf Friedrich (IV) and Charles (II) became regents of Mecklenburg. His daughter, Sophie Charlotte became the queen of Great Britain, after marrying George III.


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