American biochemist, Nobel Prize winner, AIDS denialist, climate change denialist From Wikipedia, the free encyclopedia
Kary Banks Mullis (December 28, 1944 – August 7, 2019) was an American biochemist. In 1993, he shared the Nobel Prize in Chemistry with Michael Smith for his role in discovering the development of the polymerase chain reaction (PCR).
Kary Banks Mullis | |
---|---|
Born | |
Died | August 7, 2019 74) Newport Beach, California, U.S. | (aged
Nationality | American |
Known for | development of Polymerase chain reaction |
Awards | Nobel Prize in Chemistry (1993) |
Scientific career | |
Fields | Biochemist |
The process of polymerase chain reaction (PCR) was first described by Kjell Kleppe and 1968 Nobel laureate H. Gobind Khorana. It allows specific DNA sequences to be amplified (multiplied). Mullis greatly improved the technique, and it became a standard tool in DNA research.[1][2]
In 1983, Mullis was working for Cetus Corp. as a chemist.[3] That spring, according to Mullis, he was driving his vehicle late one night, when he had the idea to use a pair of primers to bracket the desired DNA sequence and to copy it using DNA polymerase. This would allow a small strand of DNA to be copied almost an infinite number of times.[3] Cetus took Mullis off his usual projects to concentrate on PCR full-time.[3] Mullis succeeded in demonstrating PCR on December 16, 1983.
Cetus paid him a mere $10,000 for the discovery but later sold it to Hoffmann-La Roche, owned by Roche Holding Ltd., for $300 million.[4]
Mullis died on August 7, 2019 from pneumonia in Newport Beach, California at the age of 74.[5]
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