infectious disease From Wikipedia, the free encyclopedia
Diphtheria (pronounced "diff-THEER-ee-uh") is an infectious disease caused by a bacterium called Corynebacterium diphtheriae. It can be treated by special drugs, or by antibiotics. There is a vaccine which can prevent diphtheria. In 1942, there were 50,804 diphtheria cases in England and Wales; now there is about one case a year.[1]
Diphtheria can cause serious problems, like:
Signs and symptoms of diphtheria usually begin two to five days after a person gets infected. They may include:
In some people, infection with diphtheria-causing bacteria causes only a mild illness. These people may have no obvious signs or symptoms. Infected people who do not know they have diphtheria are called carriers of diphtheria, because they can spread the infection without being sick themselves.
A second type of diphtheria can affect the skin. This type of diphtheria is called cutaneous diphtheria. It causes pain, redness, and swelling on the skin, like other bacterial skin infections. People with cutaneous diphtheria may get ulcers, covered by a gray membrane, on their skin.
Cutaneous diphtheria is more common in tropical climates. However, cutaneous diphtheria also happens in the United States, especially among people with poor hygiene who live in crowded conditions.
Diphtheria toxin is produced by C. diphtheriae only when infected with a bacteriophage which integrates the toxin-encoding genetic elements into the bacteria.[2][3]
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