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Methamphetamine
stimulant drug / From Wikipedia, the free encyclopedia
Methamphetamine (also called meth or speed) is a man-made stimulant drug.[13][14] It is highly addictive and the first time experience may get the person addicted (drug dependent). Many people use it as an illegal drug, but it is also used legally by prescription to treat attention-deficit hyperactivity disorder (ADHD) or obesity as "Desoxyn".[13][15][16]
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Pronunciation | /ˌmɛθæmˈfɛtəmiːn/ (METH-am-FET-ə-meen), /ˌmɛθəmˈfɛtəmiːn/ (METH-əm-FET-ə-meen), /ˌmɛθəmˈfɛtəmən/ (METH-əm-FET-ə-mən)[1] | ||
Trade names | Desoxyn, Methedrine | ||
Synonyms | N-methylamphetamine, N,α-dimethylphenethylamine, desoxyephedrine | ||
AHFS/Drugs.com | Monograph | ||
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Dependence liability | Physical: None Psychological: Very High | ||
Addiction liability | Very High | ||
Routes of administration | Medical: oral (swallowed) Recreational: oral, intravenous (injected) to vein, intramuscular (injected) to muscle, subcutaneous (injected) under skin, vapour inhalation, insufflation (inhaled), rectal (anal), vaginal (into vagina) | ||
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Bioavailability | Oral: 67%[3][4][5][6] Intranasal: 79%[3][4] Inhalation: 67–90%[3][4][5] Intravenous: 100%[3][6] | ||
Protein binding | Varies widely[7] | ||
Metabolism | Processed in (liver) CYP2D6[8][9] and FMO3[10][11] | ||
Metabolites | • Amphetamine • Pholedrine • N-Hydroxymethamphetamine | ||
Onset of action | Oral: 3 hours (peak)[3] Intranasal: <15 minutes[3] Inhalation: <18 minutes[3][4] Intravenous: <15 minutes[3] | ||
Elimination half-life | 9–12 hours (range 5–30 hours) (irrespective of route)[4][3] | ||
Duration of action | 8–12 hours[5] | ||
Excretion | Exits mostly through kidney | ||
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ECHA InfoCard | 100.007.882 ![]() | ||
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Formula | C10H15N | ||
Molar mass | 149.24 g·mol−1 | ||
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Chirality | Racemic mixture | ||
Melting point | 170 °C (338 °F) [12] | ||
Boiling point | 212 °C (414 °F) at 760 mmHg[12] | ||
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Methamphetamine has two isomers, "left-handed" and "right-handed". Left-handed methamphetamine helps fight stuffy nose and is legal. Right-handed methamphetamine makes people feel high and is mostly illegal. This page is mostly about the right-handed form.
Methamphetamine is very addictive.[14] This means that when people start taking the drug, they will want to keep taking more, even if it is making them sick.
Methamphetamine can be in pill, powder or crystal form, and can be snorted, smoked, injected, or eaten.[17][18] In its smoked form, methamphetamine is known as "ice," "crystal," "crank," "batu," "barang," "cerita," or "glass".
Eating methamphetamine (oral route) involves swallowing the tablets or powder. Injections can be done into a vein, muscle, or under a pinched bit of skin (subcutaneous). It can (usually in crystal form) be heated and the vapours inhaled using special pipes. Using tablets as a suppository means inserting them into the body not by mouth. Methamphetamine can be inserted into the rectal cavity (bum) or vagina.