Acil-KoA dehidrogenaza

Acil-KoA dehidrogenaza (EC 1.3.99.3, acilna dehidrogenaza, masna acil koenzim A dehidrogenaza, acil koenzim A dehidrogenaza, masna-acil-KoA dehidrogenaza, acil KoA dehidrogenaza, general acil KoA dehidrogenaza, acil lanca srednje dužine koenzim A dehidrogenaza, acil lanca srednje dužine KoA dehidrogenaza, acil-KoA:(akceptor) 2,3-oksidoreduktaza) je enzim sa sistematskim imenom acil-KoA:akceptor 2,3-oksidoreduktaza.^[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju:

acil-KoA + akceptor ${\displaystyle \rightleftharpoons }$ 2,3-dehidroacil-KoA + redukovani akceptor

Acil-KoA dehidrogenaza
Identifikatori
EC broj	1.3.99.3
CAS broj	9027-65-0
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Ovaj flavoprotein je deo sistema koji redukuje ubihinon i druge akceptore.

Reference

1. Beinert, H. (1963). „Acyl coenzyme A dehydrogenase”. u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 7 (2nd izd.). New York: Academic Press. str. 447-466.
2. Crane, F.L., Mii, S., Hauge, J.G., Green, D.E. and Beinert, H. (1956). „On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. I. The general fatty acyl coenzyme A dehydrogenase”. J. Biol. Chem. 218: 701-716. PMID 13295224.
3. Hauge, J.G., Crane, F.L. and Beinert, H. (1956). „On the mechanism of dehydrogenation of fatty acyl derivatives of coenzyme A. III. Palmityl CoA dehydrogenase”. J. Biol. Chem. 219: 727-733. PMID 13319294.

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Vanjske veze

• MeSH Acyl-CoA+dehydrogenase