H+ transportujuća dvosektorna ATPaza

H⁺ transportujuća dvosektorna ATPaza (EC 3.6.3.14, ATP sintaza, F1-ATPaza, FoF1-ATPaza, H⁺-transportna ATPaza, mitohondrijska ATPaza, faktori sprezanja (F0, F1 i CF1), hloroplastna ATPaza, bakterijska Ca²⁺/Mg²⁺ ATPaza) je enzim sa sistematskim imenom ATP fosfohidrolaza (H⁺ transport).^[1][2][3]</ref>^[4] Ovaj enzim katalizuje sledeću hemijsku reakciju

ATP + H₂O + H⁺_in ${\displaystyle \rightleftharpoons }$ ADP + fosfat + H⁺_out

H+ transportujuća dvosektorna ATPaza
Identifikatori
EC broj	3.6.3.14
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB	RCSB PDB PDBe PDBj PDBsum
Pretraga PMC articles PubMed articles NCBI Protein search

Ova multipodjednična nefosforilisana ATPaza učestvuje u transportu jona.

Reference

1. Boyer, P.D. (1993). „The binding change mechanism for ATP synthase - some probabilities and possibilities”. Biochim. Biophys. Acta 1140: 215-250. PMID 8417777.
2. Abrahams, J.P., Leslie, A.G.W., Lutter, R. and Walker, J.F. (1994). „Structure at 2.8 Å resolution of F₁-ATPase from bovine heart mitochondria”. Nature 375: 621-628. PMID 8065448.
3. Blair, A., Ngo, L., Park, J., Paulsen, I.T. and Saier, M.H., Jr. (1996). „Phylogenetic analyses of the homologous transmembrane channel-forming proteins of the F0F1-ATPases of bacteria, chloroplasts and mitochondria”. Microbiology 142: 17-32. PMID 8581162.
4. Noji, H., Yasuda, R., Yoshida, M. and Kinosita, K., Jr. (1997). „Direct observation of the rotation of F₁-ATPase”. Nature 386: 299-302. PMID 9069291.

Literatura

• Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
• Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
• Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
• Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
• Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
• Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.

Spoljašnje veze

• MeSH H+-transporting+two-sector+ATPase