en:CYP3A4, as well as conjugative by en:glucuronidation (en:UGT2B7) and en:sulfation; no active metabolites exist 생물학적 반감기 1.2–2 hr (35% of the drug enters
albumin) 동등생물의약품 ? 약물 대사 Liver (mostly CYP450-independent (reduction, sulfation, and cleavage of lactone ring), some CYP3A4 contribution) 생물학적 반감기 25–33