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Usus gedhé utawa kolon ing anatomi iku pérangan usus antarané usus buntu lan rektum. Fungsi mligi organ iki yaiku nyerep banyu saka feses. Ing mamalia, kolon kapérang saka kolon munggah (ascending), kolon malang (transverse), kolon mudhun (descending), kolon sigmoid, lan rektum. Pérangan kolon saka usus buntu tekan tengahing kolon malang asring sinebut "kolon tengen", éwadéné pérangan sisané asring sinebut "kolon kiwa".
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