Protease inhibitor (pharmacology)

プロテアーゼ (protease)は、タンパク質をより小さなポリペプチドや単一のアミノ酸への分解を触媒する (速度を上げる) 加水分解酵素の総称である。ペプチダーゼ (peptidase) やプロテイナーゼ（proteinase）とも呼ばれる。それらは、水が反応して結合を壊す加水分解によってタンパク

(1980). “Intracellular Ca2+-dependent protease (calpain) and its high-molecular-weight endogenous inhibitor (calpastatin)”. Advances in Enzyme Regulation

ordering of the Fas-apoptotic pathway: the Fas/APO-1 protease Mch5 is a CrmA-inhibitable protease that activates multiple Ced-3/ICE-like cysteine proteases”

effects on human immunodeficiency virus protease inhibitor clearance and cellular accumulation”. Clinical Pharmacology and Therapeutics 80 (4): 307–18. (October

boosts the intestinal absorption of transport substrates, including HIV protease inhibitors and GS-7340, in vitro”. Antimicrobial Agents and Chemotherapy