Huntingtin-associated protein 1

PMID 9325248.  ^ “Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi”. Nat. Cell Biol. 4 (2): 95–105

“Demonstration of a role for alpha-synuclein as a functional microtubule-associated protein”. J. Alzheimers Dis. 6 (4): 435?42; discussion 443?9. PMID 15345814

myodegenerative conformational disorder associated with Abeta, protein misfolding, and proteasome inhibition”. Neurology 66 (2 Suppl 1): S39-48. doi:10.1212/01.wnl

HEATの名前は、このリピート配列を共有する代表的な4つのタンパク質の頭文字に由来する：Huntingtin (ハンチントン病の責任タンパク質ハンチンチン), Elongation factor 3 (EF3)（タンパク質合成伸長因子）, Protein phosphatase 2A (PP2A) A

glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin”. The European Journal of Neuroscience