Menteri Luar Negeri (外務大臣, Gaimu daijin) Jepang adalah menteri anggota Kabinet Jepang yang bertanggung jawab untuk urusan luar negeri dan pemimpin Kementerian Urusan Luar Negeri.
Pejabat Menteri Luar Negeri Jepang yang sekarang adalah Takeshi Iwaya sejak 2024.
- Inoue Kaoru (1885-1887)
- Ito Hirobumi (1887-1888)
- Okuma Shigenobu (1888-1889, 1896-1897, 1898, 1915)
- Aoki Shuzo (1889-1891, 1898-1900)
- Enomoto Takeaki (1891-1892)
- Mutsu Munemitsu (1892-1896)
- Saionji Kimmochi (1896, 1906)
- Nishi Tokujiro (1897-1898)
- Kato Takaaki (1900-1901, 1906, 1913, 1914-1915)
- Sone Kosuke (1901)
- Komura Jutaro (1901-1906, 1908-1911)
- Hayashi Tadasu (1906-1908)
- Terauchi Masatake (1908, 1916)
- Yasuya Uchida (1911-1912, 1918-1923, 1932-1933)
- Taro Katsura (1912-1913)
- Makino Nobuaki (1913-1914)
- Kikujiro Ishii (1915-1916)
- Ichiro Motono (1916-1918)
- Shimpei Goto (1918)
- Gonnohyoe Yamamoto (1923)
- Hikokichi Ijuin (1923-1924)
- Keishiro Matsui (1924)
- Kijuro Shidehara (1924-1927, 1929-1931)
- Giichi Tanaka (1927-1929)
- Tsuyoshi Inukai (1931-1932)
- Kenkichi Yoshizawa (1932)
- Makoto Saito (1932)
- Koki Hirota (1933-1936, 1937-1938)
- Hachiro Arita (1936-1937, 1938-1939, 1940)
- Senjuro Hayashi (1937)
- Naotake Sato (1937)
- Kazushige Ugaki (1938)
- Nobuyuki Abe (1939)
- Kichisaburo Nomura (1939–1940)
- Yosuke Matsuoka (1940-1941)
- Teijiro Toyoda (1941)
- Shigenori Togo (1941-1942, 1945)
- Hideki Tojo (1942)
- Masayuki Tani (1942-1943)
- Mamoru Shigemitsu (1943-1945, 1945, 1954-1956)
- Kantaro Suzuki (1945)
- Shigeru Yoshida (1945-1947, 1948-1954)
- Hitoshi Ashida (1947-1948)
- Nobusuke Kishi (1956-1957)
- Aiichiro Fujiyama (1957-1960)
- Zentaro Kosaka (1960-1962, 1976)
- Masayoshi Ohira (1962-1964, 1972-1974)
- Etsusaburo Shiina (1964-1966)
- Takeo Miki (1966-1968)
- Kiichi Aichi (1968-1971)
- Takeo Fukuda (1971-1972)
- Toshio Kimura (1974)
- Kiichi Miyazawa (1974-1976)
- Iichiro Hatoyama (1976-1977)
- Sunao Sonoda (1977-1979, 1981)
- Saburo Okita (1979-1980)
- Masayoshi Ito (1980-1981)
- Yoshio Sakurauchi (1981-1982)
- Shintaro Abe (1982-1986)
- Tadashi Kuranari (1986-1987)
- Sosuke Uno (1987-1989)
- Hiroshi Mitsuzuka (1989)
- Taro Nakayama (1989-1991)
- Michio Watanabe (1991-1993)
- Kabun Muto (1993)
- Tsutomu Hata (1993-1994)
- Koji Kakizawa (1994)
- Yohei Kono (1994-1996, 1999-2001)
- Yukihiko Ikeda (1996-1997)
- Keizo Obuchi (1997-1998)
- Masahiko Komura (1998-1999)
- Makiko Tanaka (2001-2002)
- Junichiro Koizumi (2002)
- Yoriko Kawaguchi (2002-2004)
- Nobutaka Machimura (2004-2005)
- Taro Aso (2005-2007)
- Nobutaka Machimura (2007)
- Masahiko Kōmura (2007-2008)
- Hirofumi Nakasone (2008–2009)
- Katsuya Okada (2009–2010)
- Seiji Maehara (2010–2011)
- Yukio Edano (pelaksana tugas; 2011)
- Takeaki Matsumoto (2011)
- Kōichirō Genba (2011–2012)
- Fumio Kishida (2012–2017)
- Tarō Kōno (2017–2019)
- Toshimitsu Motegi (2019–2021)
- Fumio Kishida (pelaksana tugas; 2021)
- Yoshimasa Hayashi (2021–2023)
- Yōko Kamikawa (2023–2024)
- Takeshi Iwaya (2024–sekarang)