John Alberto Leguizamo (lahir 22 Juli 1964
) merupakan seorang aktor berkebangsaan Kolombia yang memenangkan nominasi Emmy Award dan Golden Globe. Dia dilahirkan di Bogota. Dia berkarier di dunia film sejak tahun 1984.
- "Chef" (2014)
- Ice Age: Dawn of the Dinosaurs (2009)
- Nothing Like the Holidays (2008)
- Game (2008)
- Miracle at St. Anna (2008)
- Righteous Kill (2008)
- The Happening (2008)
- The Ministers (2008)
- Paraiso Travel (2008)
- The Take (2008)
- The Babysitters (2007)
- Love in the Time of Cholera (2007)
- The Kill Point (2007) (serial TV)
- My Name Is Earl (2006)
- Ice Age: The Meltdown (2006)
- The Alibi (2006)
- The Groomsmen (2006)
- ER (TV Series) (2005)
- Land of the Dead (2005)
- Sueño (2005)
- The Honeymooners (2005)
- Assault on Precinct 13 (2005)
- Crónicas (2004)
- Undefeated (film HBO) (2003)
- Ice Age (2002)
- Collateral Damage (2002)
- Point of Origin (film HBO) (2002)
- Empire (2002)
- Spun (2002)
- Moulin Rouge! (2001)
- What's The Worst That Could Happen? (2001)
- Arabian Nights (2000) (film TV)
- Titan A.E. (2000) (suara)
- King of the Jungle (2000)
- Summer of Sam (1999)
- Frogs For Snakes (1998)
- Dr. Dolittle (1998)
- Freak (1998)
- The Pest (1997)
- Spawn (1997)
- A Brother's Kiss (1997)
- Romeo + Juliet (1996)
- The Fan (1996)
- Executive Decision (1996)
- A Pyromaniac's Love Story (1995)
- To Wong Foo, Thanks for Everything! Julie Newmar (1995)
- Carlito's Way (1993)
- Super Mario Bros. (1993)
- Night Owl (a.k.a. "Nite Owl") (1993)
- Whispers in the Dark (1992)
- Regarding Henry (1991)
- Hangin' with the Homeboys (1991)
- Die Hard 2: Die Harder (1990)
- Revenge (1990)
- Casualties of War (1989)
- Mixed Blood (1985)