James Hugh Calum Laurie (lahir 11 Juni 1959
) adalah seorang aktor berkebangsaan Inggris. Dia menjadi yang terkenal di Britania Raya, Republik Irlandia, negara-negara Persemakmuran seperti Australia, Selandia Baru, dan sebagian di Eropa. Dia dilahirkan di Oxford, Britania Raya. Dia mulai berkarier di dunia film sejak tahun 1982. Hugh Laurie mulai terkenal setelah bermain dalam serial Blackadder bersama Rowan Atkinson.
- Cambridge Footlights Revue (1982) - various characters
- Alfresco (1983–1984) - writer/various characters
- The Crystal Cube (1983) - Max Belhaven/various characters
- The Young Ones (1984) - Lord Monty
- Plenty (1985) - Michael
- Mrs. Capper's Birthday (1985) - Bobby
- Happy Families (1985) - Jim
- Blackadder II (1986) - Simon Partridge (also known as Mr Ostrich & Farters Parters), Prince Ludwig the Indestructible
- Happy Families (1985) - Jim
- Filthy Rich & Catflap (1986) - N'Bend
- Blackadder the Third (1987) - George, Prince of Wales, Prince Regent
- A Bit of Fry and Laurie (1989–1995) - writer/various characters
- Blackadder Goes Forth (1989) - Lt the Honourable George Colhurst St Barleigh
- The New Statesman (1989) - Waiter
- Jeeves and Wooster (1990–1993) - Bertie Wooster
- Peter's Friends (1992) - Roger Charleston
- Sense and Sensibility (1995) - Mr Palmer
- Tracey Takes On... (1996) - Timothy Bugge (Season 1)
- 101 Dalmatians (1996) - Jasper
- Spiceworld (1997) - Poirot
- The Borrowers (1997) - Police Officer Steady
- The Bill (1998)
- The Man in the Iron Mask (1998) - Pierre, The King's Advisor
- Cousin Bette (1998) - Baron Hector Hulot
- Blackadder: Back & Forth (1999) - Viscount George Bufton-Tufton/Georgius
- Stuart Little (1999) - Mr Fredrick Little
- Maybe Baby (2000) - Sam Bell
- Chica de Río (2001) - Raymond
- Life with Judy Garland: Me and My Shadows (2001) - Vincente Minnelli
- Stuart Little 2 (2002) - Mr. Frederick Little
- Spooks (2002) - Jools Siviter
- Fortysomething - Paul Slippery
- Fire Engine Fred (2004)
- Flight of the Phoenix (2004) - Ian
- House (2004–present) - Dr Gregory House
- Valiant (2005) - Wing Commander Gutsy (voice)
- Stuart Little 3: Call of the Wild (2006) - Mr. Frederick Little (voice)
- The Night Watchman (2008) - Internal Affairs Officer
- Arthur Christmas - Steve (suara)