گیرنده ۵ سوماتوستاتین

گیرنده ۵ سوماتوستاتین (انگلیسی: Somatostatin receptor 5) پروتئینی است که در انسان توسط ژن «SSTR5» کُد می‌شود.^[4]

SSTR5
معین‌کننده‌ها
نام‌های دیگر	SSTR5, SS-5-R, Somatostatin receptor 5
شناسه‌های بیرونی	MGI: 894282 HomoloGene: 20287 GeneCards: SSTR5
موقعیت ژن (موش) کروموزوم کروموزوم ۱۷ (موش)[1] نوار 17 A3.3|17 12.62 cM شروع 25,708,849 bp[1] پایان 25,716,262 bp[1]
الگوی گسترش RNA More reference expression data
هستی‌شناسی ژن عملکرد ملکولی • neuropeptide binding • G protein-coupled receptor activity • signal transducer activity • somatostatin receptor activity • peptide binding ترکیبات سلولی • integral component of membrane • neuron projection • پوسته یاخته • integral component of plasma membrane • membrane فرایند زیستی • positive regulation of cytokinesis • G protein-coupled receptor signaling pathway • G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • glucose homeostasis • GO:0072468 ورارسانی پیام • negative regulation of cell population proliferation • regulation of insulin secretion • somatostatin signaling pathway • chemical synaptic transmission • cellular response to glucocorticoid stimulus • neuropeptide signaling pathway منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌ها	انسان	موش
Entrez	6755	20609
آنسامبل	ENSG00000162009	ENSMUSG00000050824
یونی‌پروت	P35346	O08858
RefSeq (mRNA)	NM_001172560، NM_001172572، NM_001172573 NM_001053، NM_001172560، NM_001172572، NM_001172573	NM_011425 NM_001191008، NM_011425
RefSeq (پروتئین)	NP_001166031 NP_001044، NP_001166031	NP_035555 NP_001177937، NP_035555
موقعیت (UCSC)	ن/م	Chr : 25.71 – 25.72 Mb
جستجوی PubMed	[2]	[3]
ویکی‌داده
مشاهده/ویرایش انسان مشاهده/ویرایش موش

این گیرنده، متعلق به یک ابرخانواده از گیرنده‌هاست که ۷ بخش تراغشایی دارد.

منابع

1. GRCm38: Ensembl release 89: ENSMUSG00000050824 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. Takeda J, Fernald AA, Yamagata K, Le Beau MM, Bell GI (Aug 1995). "Localization of human somatostatin receptor 5 gene (SSTR5) to chromosome band 16p13.3 by fluorescence in situ hybridization". Genomics. 26 (3): 638–9. doi:10.1016/0888-7543(95)80195-R. PMID 7607700.

• مشارکت‌کنندگان ویکی‌پدیا. «Somatostatin receptor 5». در دانشنامهٔ ویکی‌پدیای انگلیسی، بازبینی‌شده در ۱۲ دسامبر ۲۰۱۷.

بیشتر بخوانید

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• Sharma K, Patel YC, Srikant CB (1999). "C-terminal region of human somatostatin receptor 5 is required for induction of Rb and G1 cell cycle arrest". Mol. Endocrinol. 13 (1): 82–90. doi:10.1210/me.13.1.82. PMID 9892014.
• Kumar U, Sasi R, Suresh S, et al. (1999). "Subtype-selective expression of the five somatostatin receptors (hSSTR1-5) in human pancreatic islet cells: a quantitative double-label immunohistochemical analysis". Diabetes. 48 (1): 77–85. doi:10.2337/diabetes.48.1.77. PMID 9892225.
• Rocheville M, Lange DC, Kumar U, et al. (2000). "Subtypes of the somatostatin receptor assemble as functional homo- and heterodimers". J. Biol. Chem. 275 (11): 7862–9. doi:10.1074/jbc.275.11.7862. PMID 10713101.
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• Daniels RJ, Peden JF, Lloyd C, et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. doi:10.1093/hmg/10.4.339. PMID 11157797.
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پیوند به بیرون

• somatostatin receptor 5 در سرعنوان‌های موضوعی پزشکی (MeSH) در کتابخانهٔ ملی پزشکی ایالات متحدهٔ آمریکا