Otsaju ehk telentsefalon (ladina telencephalon ) on kesknärvisüsteemiga loomadel embrüonaalses arengujärgus ajuosa, mis moodustub prosentsefalonist.[1]
Koos vaheajuga on ta eesaju (prosencephalon) osa.
Otsaju on sekundaarsetest ajupõitest esimene, sellest areneb suuraju.
Madude embrüotel on otsaju tuvastatav üsna kohe peale munade väljutamist.
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