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Silibinin
Chemical compound / From Wikipedia, the free encyclopedia
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Silibinin (INN), also known as silybin (both from Silybum, the generic name of the plant from which it is extracted), is the major active constituent of silymarin, a standardized extract of the milk thistle, containing a mixture of flavonolignans consisting of silibinin, isosilibinin, silychristin, silidianin, and others. Silibinin itself is a mixture of two diastereomers, silybin A and silybin B, in approximately equimolar ratio.[1] Silibinin is used in pure forms as a medication, and more frequently as an active ingredient in milk thistle–derived herbal supplements.
Quick Facts Clinical data, AHFS/Drugs.com ...
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![]() Silibinin A and silibinin B structures | |
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AHFS/Drugs.com | International Drug Names |
Routes of administration | Oral and Intravenous |
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ECHA InfoCard | 100.041.168 ![]() |
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Formula | C25H22O10 |
Molar mass | 482.441 g·mol−1 |
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