Pomalidomide
Chemical compound / From Wikipedia, the free encyclopedia
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Pomalidomide, sold under the brand names Pomalyst and Imnovid,[7][8] is an anti-cancer medication used for the treatment of multiple myeloma and AIDS-related Kaposi sarcoma.[7]
Quick Facts Clinical data, Trade names ...
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Trade names | Pomalyst, Imnovid |
AHFS/Drugs.com | Monograph |
MedlinePlus | a613030 |
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Routes of administration | By mouth |
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Bioavailability | 73% (at least)[9] |
Protein binding | 12–44% |
Metabolism | Liver (mostly CYP1A2- and CYP3A4-mediated; some minor contributions by CYP2C19 and CYP2D6) |
Elimination half-life | 7.5 hours |
Excretion | Urine (73%), faeces (15%) |
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ECHA InfoCard | 100.232.884 |
Chemical and physical data | |
Formula | C13H11N3O4 |
Molar mass | 273.248 g·mol−1 |
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Chirality | Racemic mixture |
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Pomalidomide was approved for medical use in the United States in February 2013,[10] and in the European Union in August 2013.[8] It is available as a generic medication.[11]