Wessagusset Colony was a short-lived English trading colony in New England located in Weymouth, Massachusetts. It was settled in August 1622 by between 50 and 60 colonists who were ill-prepared for colonial life. The colony was settled without adequate provisions, and was dissolved in late March 1623 after harming relations with local Indians. Surviving colonists joined Plymouth Colony or returned to England. It was the second settlement in Massachusetts, predating the Massachusetts Bay Colony by six years.