Tyngsborough is a town in northern Middlesex County, Massachusetts, United States. Tyngsborough is 28 miles (45 km) from Boston along the Route 3 corridor, and located on the New Hampshire state line. At the 2020 census, the town population was 12,380. By its location, the town serves as a suburb of neighboring cities such as Nashua, New Hampshire and Lowell, Massachusetts.