The Tree Streets Historic District is a 120-acre (49 ha) historic district in Waynesboro, Virginia. The aptly named district contains portions of Cherry, Chestnut, Locust, Maple, Oak, Pine and Walnut Avenues as well as portions of Eleventh through Sixteenth Streets and part of South Wayne Avenue. It covers the oldest residential neighborhood in Waynesboro and reflects the various stages of development of the city from the 19th century through 1951. It was listed on the National Register of Historic Places in 2002. In 2002, it included 445 buildings deemed to contribute to the historic character of the area, two contributing sites, and seven other contributing structures.