The Tohono Oʼodham High School is a high school in unincorporated Pima County, Arizona, in the Tohono Oʼodham Indian Reservation. Located along Arizona State Route 86, near Sells, it is operated directly by the Bureau of Indian Education. Feeder schools include the San Simon day school and the Santa Rosa Boarding School, also operated by the BIA. It was established in the mid-1980s as the remaining reservations in Arizona finally received their own high schools.