The Squirrel River is a 72-mile (116 km) tributary of the Kobuk River in the U.S. state of Alaska. It is a very clear, small arctic river flowing south from the foothills of Baird Mountains to where it meets the Kobuk River in the village of Kiana. From Kiana, the Kobuk flows southwest into Hotham Inlet of Kotzebue Sound on the Chukchi Sea.