Segezhsky District is an administrative district (raion), one of the fifteen in the Republic of Karelia, Russia. It is located in the east of the republic. The area of the district is 10,700 square kilometers (4,100 sq mi). Its administrative center is the town of Segezha. As of the 2010 Census, the total population of the district was 41,215, with the population of Segezha accounting for 71.9% of that number.