San Gregorio d'Ippona is a comune (municipality) in the Province of Vibo Valentia in the Italian region Calabria, located about 50 kilometres (31 mi) southwest of Catanzaro and about 2 kilometres (1 mi) southeast of Vibo Valentia. As of 31 December 2004, it had a population of 2,278 and an area of 12.4 square kilometres (4.8 sq mi).