Rancho Santa Maria de Los Peñasquitos was a 8,486-acre (34.34 km2) Mexican land grant in present-day southwestern San Diego County, California, given in 1823 to Francisco María Ruiz. The name means "Saint Mary of the Little Cliffs". It encompassed the present-day communities of Mira Mesa, Carmel Valley, and Rancho Peñasquitos in northern San Diego, and was inland from the Torrey Pines State Natural Preserve bluffs.