The province of Isernia is a province in the Molise region of Italy. The provincial capital is the city Isernia and the president of the province is Alfredo Ricci. The province of Isernia has an area of 1,535.24 square kilometres (592.76 sq mi) and a population of 86,405 inhabitants as of 2016. It contains 52 comuni in the province, listed at comuni of the province of Isernia.