Portsmouth was a fishing and shipping village located on Portsmouth Island on the Core Banks in North Carolina, United States. Portsmouth Island is a tidal island connected, under most conditions, to the northern end of the North Core Banks, across Ocracoke Inlet from the village of Ocracoke. The town lies in Carteret County, was established in 1753 by the North Carolina Colonial Assembly, and abandoned in 1971. Its remains are now part of the Cape Lookout National Seashore.