"Me Wise Magic" is a song by Van Halen that appears on the rock band's 1996 compilation album Best Of – Volume I and became the band's 13th No. 1 Billboard Mainstream Rock Track, maintaining the No. 1 position for 6 weeks during the autumn of 1996. It was the first of two highly anticipated tracks recorded by the band with its original lead vocalist and songwriter, David Lee Roth. Together with the other new song on the compilation album, "Can't Get This Stuff No More", it is the last song recorded by the original line-up, consisting of Roth, Michael Anthony and the Van Halen brothers.