Larissa is the capital and largest city of the Thessaly region in Greece. It is the fifth-most populous city in Greece with a population of 148,562 in the city proper, according to the 2021 census. It is also capital of the Larissa regional unit. It is a principal agricultural centre and a national transport hub, linked by road and rail with the port of Volos, the cities of Thessaloniki and Athens. The municipality of Larissa has 164,095 inhabitants, while the regional unit of Larissa reached a population of 268,963.