Dreghorn is a village in North Ayrshire, Scotland, 3.5 kilometres east of Irvine town centre, on the old main road from Irvine to Kilmarnock. It is sited on a ridge between two rivers. As archaeological excavations near the village centre have found a significant neolithic settlement provisionally dated to around 3500 BC, as well as medieval structures, scholars have suggested that Dreghorn could be Britain's oldest continuously inhabited village. Both Irvine and Dreghorn have grown in size and they are now separated by the Annick Valley Park, which incorporates a footpath and National Cycle Route 73 on the route of the disused Irvine to Busby railway line. It had an estimated population of 3,450 in 2022.