The Clarksville Historic District in Austin, Texas, is an area located west of downtown Austin near Lady Bird Lake and just northeast of the intersection of the Missouri Pacific Railroad and West Tenth Street. Many historic homes and structures are located within the Clarksville Historic District. While Clarksville is geographically part of the Old West Austin Historic District, it is distinct from the two historic neighborhoods of Old Enfield, which lies immediately to the north on the eastern side of Texas State Highway Loop 1, and Tarrytown, which is situated to the west and northwest on the western side of Mopac.