Catholic Central School was a private, centrally located pre-K-12 regional Catholic school in Latham, New York, within the Roman Catholic Diocese of Albany. It was formed in 2022 with the merger of Saint Ambrose elementary school in Latham with Catholic Central High School in Troy, New York. The new school is located on the grounds of the former Saint Ambrose School. The school's Troy property was put up for sale in March 2022, and was listed on the National Register of Historic Places in 2024.