Barksdale is a small unincorporated community and census-designated place (CDP) in the hill country section of the U.S. state of Texas. It is located in Edwards County. In 1990, Barksdale had 617 inhabitants and six businesses. By 2000, the population grew to 1,081 with sixteen businesses. It was first listed as a CDP in the 2020 census with a population of 91.