Virulent Newcastle disease
Contagious viral avian disease / From Wikipedia, the free encyclopedia
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Virulent Newcastle disease (VND), formerly exotic Newcastle disease,[1] is a contagious viral avian disease affecting many domestic and wild bird species; it is transmissible to humans.[2] Though it can infect humans, most cases are non-symptomatic; rarely it can cause a mild fever and influenza-like symptoms and/or conjunctivitis in humans. Its effects are most notable in domestic poultry due to their high susceptibility and the potential for severe impacts of an epizootic on the poultry industries. It is endemic to many countries. No treatment for VND is known, but the use of prophylactic vaccines[3] and sanitary measures reduces the likelihood of outbreaks.
This article needs more reliable medical references for verification or relies too heavily on primary sources. (February 2023) |
Avian orthoavulavirus 1 | |
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Avian orthoavulavirus 1 (stained in brown) in the conjunctiva of a chicken | |
Virus classification | |
(unranked): | Virus |
Realm: | Riboviria |
Kingdom: | Orthornavirae |
Phylum: | Negarnaviricota |
Class: | Monjiviricetes |
Order: | Mononegavirales |
Family: | Paramyxoviridae |
Genus: | Orthoavulavirus |
Species: | Avian orthoavulavirus 1 |
The disease is caused by Newcastle disease virus (NDV), an avulavirus. Strains of Newcastle disease virus have been used to treat cancer in humans, since the virus appears to preferentially infect and kill cancerous cells. Strains of Newcastle disease virus have also been used to create viral vector vaccine candidates against Ebola and Covid-19.[4][5]