Captopril
Antihypertensive drug of the ACE inhibitor class / From Wikipedia, the free encyclopedia
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Captopril, sold under the brand name Capoten among others, is an angiotensin-converting enzyme (ACE) inhibitor used for the treatment of hypertension and some types of congestive heart failure. Captopril was the first oral ACE inhibitor found for the treatment of hypertension.[3] It does not cause fatigue as associated with beta-blockers. Due to the adverse drug event of causing hyperkalemia, as seen with most ACE Inhibitors, the medication is usually paired with a diuretic.
Quick Facts Clinical data, Pronunciation ...
Clinical data | |
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Pronunciation | /ˈkæptəprɪl/ |
Trade names | Capoten, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682823 |
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Routes of administration | By mouth |
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Bioavailability | 70–75% |
Metabolism | Liver |
Elimination half-life | 1.9 hours |
Excretion | Kidney |
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ECHA InfoCard | 100.057.806 |
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Formula | C9H15NO3S |
Molar mass | 217.28 g·mol−1 |
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Captopril was patented in 1976 and approved for medical use in 1980.[4]