Stem-loops are nucleic acid secondary structural elements which form via intramolecular base pairing in single-stranded DNA or RNA. They are also referred
sequence whose structure is known. Because loops have highly variable sequences even within a given structural motif or protein fold, they often correspond
internal loop motif: a new RNA structural element that forms a cross-strand AAA stack and long-range tertiary interactions". Journal of Molecular Biology. 360
term structural has the same meaning as in structuralbiology, and structural bioinformatics can be seen as a part of computational structuralbiology. The
The T-loop motif has been identified as a ubiquitous structural element in a number of noncoding RNAs. At least one other instance of the T-loop, found